Two in-vitro skin irritation tests endorsed

The ECVAM Scientific Advisory Committee (ESAC) has endorsed the scientific validity of two further in-vitro skin irritation tests on its 29th meeting held in November 2008.

Both models (SkinEthic RHE and EpiDerm SIT) are based on reconstructed human epiderms and measure or predict the same biological or toxic effect as the fully validated and accepted reference method.

Detailed information can be found on the ECVAM's website NEWS/EVENTS and MEETINGS section.

Please note that any test method submitted to or validated by ECVAM must be reviewed and endorsed by its Scientific Advisory Committee before they can be used within the regulatory framework.

As soon as more background documentation will become available for public access, we will update the website and inform you.


Institute for Health and Consumer Protection (IHCP)

DG Joint Research Centre (DG JRC)







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